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KMID : 0615720100270040099
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Jouranl of Korean Acupuncture and Moxibustion society
2010 Volume.27 No. 4 p.99 ~ p.114
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Effects of Phamacopuncture with RUBI FRUCTUS Infusion Solution at KI10 on Osteoporotic Rats Induced by Ovariectomy
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Shin Hee-Woong
Lee Hyun
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Abstract
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Objectives : The purpose of this study is to observe the effects of RUBI FRUCTUS phamacopuncture infusion solution at KI10 on osteoporotic Rats Induced by ovariectomy.
Methods : The author performed several experimental items to analyze cytotoxic, osteoporosis evalu- ation, change of ALP, creatinine, Ca, P, osteocalcin, Ca/P ratio and histological change of serum and tibia.
Results : 1. Creatinine and phosphorus in serum was decreased significantly in RF-HA than control group. 2. Calcium and phosphorus in tibia was increased significantly in RF-HA than control group. 3. Osteoclast like cell in tibia was increased significantly in control group, decreased significantly in RF-HA. 4. In the histological study in tibia, TBT was significantly increased, GPL was significantly decreased in the RF-HA than control group.
Conclusions : This study suggested that RF-HA at KI10 has significant effect on osteoporosis.
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KEYWORD
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Osteoporosis, phamacopuncture, RUBI FRUCTUS, KI10, Phosphorus, Osteoclast Like cell
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